CALL FOR TECHNOLOGY TRANSFER – EXPRESSION OF INTEREST (EOI)
SCTIMST – BMT Wing is actively engaged in applied and translational research in areas of biomedical devices, biologics and biomaterials since late 1970s. The technologies developed indigenously by SCTIMST have been transferred to several industries, which have benefitted both the industry and society at large. Our record is marked with development of innovative and popular products such as the artificial heart valve ( TTK Healthcare Ltd), blood bags ( Peninsula polymers, now Terumo Penpol Ltd, HLL Lifecare Ltd), hydrocephalus shunt (HLL Lifecare Ltd), membrane oxygenator& cardiotomy reservoirs (SIDD Lifesciences Ltd), bio ceramic composites for dental and orthopedic applications ( Basic Healthcare Ltd, IFGL Refractories Ltd,), dental composites ( Anabond Stedmann Pharma Ltd), Intrauterine Device (HLL Lifecare Ltd), vein viewer (Agappe Diagnostics Ltd), Chitra Emergency Breathing Assist Device (Wipro enterprises pvt ltd) Multiplex RT PCR kit which targets two SARS COV2 genes RdRp and ORFb- nsp14 and the human RNAse gene as the internal control ( Huwel lifesciences pvt ltd), Chitra RNA isolation kit ( Agappe diagnostics ltd), Bone cement (Onyx medicals pvt ltd ) etc to name a few.
Also post Technology Transfer activities are ongoing for many more products like ASD occlusion device, flow diverter stent, LVAD,cholecyst derived scaffold for wound dressing applications, Diagnostic kit with antibiogram for Urinary Tract Infection (UTI), Tuberculosis screening device, PT/INR monitoring device, injectable hydrogel for cartilage repair, lint free absorbent wound dressing etc.
Last date : 15th March 2022
TECHNOLOGY TRANSFER – EXPRESSION OF INTEREST (EOI)
SCTIMST is now offering technologies for licensing to enterprises including start ups for further scaling up and commercialization. These technologies are available in different stages of readiness levels such as proof of concept, pre-clinical / clinical evaluation. The technologies can be licensed either on exclusive or non-exclusive basis against payment of a combination of up-front lump sum fee and annual royalties, which will vary from product to product. Information on the technologies currently available for licensing may be viewed from the right side links.
Those interested are encouraged to contact Technology Business Division on phone - 0471-2520309/308 or email: tbd@sctimst.ac.in for further information or clarifications on the above and to facilitate visits and detailed discussions.
Interested parties may submit EoI proposals in the specified format(Annexure 1,2 & 3) indicating the technology/product of interest addressed to Head, BMT Wing, SCTIMST, Poojapura, Trivandrum-695012, latest by 12:00 noon on 15th March 2022 as signed hard copy.
Technology/Product Details
1. Implantable Micro Infusion Pump
Device Classification:
Class D
Technology Readiness Level:
TRL4
Active programmable device to automatically deliver bolus or basal quantity of drug to the region of interest within human body such as peritoneal cavity, spinal cord or other diseased regions
Key Characteristics
Configuration: Programmable
Flow Regime: Variable
Discharge Regime: Bolus/Basal/Priming
Patent Filed for "Implantable Micro Infusion Pump with Residual Volume Measurement" Patent Application No. 202041045741
Design Registration - "Collapsible type implantable infusion pump reservoir with magnetic locator, residual volume detector and needle stopper. Reg no 341393-001
The following evaluations as per ISO 14708-4 (Implants for surgery — Active implantable medical devices — Part 4: Implantable infusion pumps) are carried out to evaluate the performance and characteristics:
Minimum, Maximum flow characteristics
Accuracy, Repeatability & Reproducibility
Refill characteristics Test
Septum Puncture Test
Temperature Rise Test
Catheter Tensile Strength Test
Catheter Flexural Strength Test
Reservoir Pressure Test
Pump Tubing Durability Test
Pump Drive Durability Test
Leakage Characteristics Test
Atmospheric pressure Variation Test
Environment temperature variations Test
Fluid viscosity variation Test
Catheter Slit Opening Pressure Test
Battery Discharge Test
Device Electrical Characteristics Test
Wireless recharge characteristics
Biocompatibility Evaluations as per ISO 10993
Following activities to be carried out by Industry:
Preclinical Evaluations
Drug interactions studies
Clinical trials
Packaging
Regulatory documentation and submissions
Technology Transfer document with details on materials & consumables, equipment & utilities, SOPs / detailed procedures. Quality assurance, handling properties at the current level of development.
Training on the know how
Data on the evaluations done
2. Bioink for 3D Bioprinting
An optimized formulation of bioink prepolymer that has been modified with UV protective biomolecules standardized for 3D bioprinting applications
A hydrogel formulation with following properties
Cell friendly
Easily soluble
Photo crosslinkable
Novel UV safe formulation
3D printable
Adjustable fluidity
Consistent performance
Porous
Biodegradable
Enzyme digestible
Storage : 25oC ± 2oC
Batch size: 200 g per month with 60% yield (lab level)
One Indian patent application filed
Three publications
The following evaluations are done:
1HNMR, Degree of functionalization, Rheology, Crosslinking, In vitro Cytotoxicity – Direct contact, Test on Extract
Printability
Packing, sterilization and marketing
Technology Transfer document with details on materials and consumables, equipment & utilities, SOPs / detailed procedures. Quality assurance, handling properties.
Training on the manufacture of the product
Data on the evaluations done